Spatiotemporal delivery of bone morphogenetic protein enhances functional repair of segmental bone defects
نویسندگان
چکیده
منابع مشابه
Hydrogel Delivery of Mesenchymal Stem Cell–Expressing Bone Morphogenetic Protein-2 Enhances Bone Defect Repair
BACKGROUND The application of bone tissue engineering for repairing bone defects has gradually shown some satisfactory progress. One of the concerns raising scientific attention is the poor supply of growth factors. A number of growth factor delivery approaches have been developed for promoting bone formation. However, there is no systematic comparison of those approaches on efficiency of neobo...
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BACKGROUND Common cell based strategies for the treatment of osseous defects require the isolation and expansion of autologous cells. Since this makes such approaches time-consuming and expensive, we developed a novel expedited technology creating gene activated muscle grafts. We have previously shown that large segmental bone defects in rats can be regenerated by implantation of muscle tissue ...
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ژورنال
عنوان ژورنال: Bone
سال: 2011
ISSN: 8756-3282
DOI: 10.1016/j.bone.2011.05.010